Green Global
Foundation   Journal
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HYPOGLYCEMIC EFFECT OF METHANOLIC EXTRACT FROM FRUITS OF Sonneratia caseolaris - A MANGROVE PLANT FROM BAGERHAT REGION, THE SUNDARBANS, BANGLADESH (Pages : 1 - 6)

The present study was designed to investigate the hypoglecemic activity for the methanolic (85%) extract of mature fruits from Sonneratia caseolaris. Hypoglycemic tests were done on Swiss albino mice which were administered with the extract at the dose of 50, 100, 200 and 400 mg/kg body weight respectively in different experimental groups. The mice were sacrificed followed by oral glucose treatment and their sera were collected for glucose level analysis. The results showed that the extract was able to decrease blood glucose levels. The methanolic extract of fruits of S. caseolaris exhibited statistically significant (p<0.01 & p<0.1) reduction of serum glucose at the dose of 50, 100, 200 and 400 mg/kg-bodyweight in white albino mice (Swiss-webstar strain) at oral glucose test whereas the controlled use of glibenclamide showed the significant result (p<0.1). Our findings are in good agreement with the usage of this plant in anti-diabetic activities in ethnomedicine and provide insight for further research.Download