Green Global
Foundation   Journal
...an emerging window for scientific research and publication across the globe

DETECTION OF THE ANTIBODY TITER OF GOATPOX VACCINE DEVELOPED BY BLRI IN THE KHULNA REGION, BANGLADESH (Pages : 73 - 80)

Goatpox is a highly contagious viral disease of goats. The disease is caused mainly by Goatpox virus (GPV) and occasionally by Sheep pox virus (SPV) which is enveloped by double stranded DNA viruses, classified in the genus Capripoxvirus of the family Poxvirade. The objective of the research work was to conduct an efficacy trail of Goatpox vaccine BLRI-4505 on selected goats of Khulna region developed by Bangladesh Livestock Research Institute (BLRI). BLRI developed GPV vaccine was injected into 30 goats of selected farmers in a village of Khulna, to observe the physiological condition and the effects of the vaccine. Rectal temperatures of the experimental animals were recorded for before vaccination and seven day after vaccination. Blood was collected on before vaccination (0-Day), 15th and 30th day of post-vaccination period. Separated serum was used for C-ELISA (Enzyme Immune Slide Assay) to determine the antibody titre of vaccinated goats. Hyper-immune serum (several time vaccinated goats) was collected from BLRI experimental goats. Hyper-immune serum was used as a standard. Temperature fluctuations of the vaccinated goats were normal and no uneven effects were found. OD value of antibody titre was satisfactory level and increased in day 30 than day- 0 and day- 15. This experiment reveals that newly developed GPV vaccine is effective against Goatpox virus in Bangladesh and few more trials in the intensive and semi-intensive goat populated areas would be better about the efficacy result of the vaccine.Download