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SUSCEPTIBILITY OF Escherichia coli ISOLATED FROM BLOOD STREAM (Pages : 34 - 37)

. N. HASAN, M. J. MAHAL, S. M. MOU, A.H.M. SHAMIM KABIR AND M. J. ISLAM

The prospective study was conducted in IBN SINA Diagnostics and Imaging center, Dhaka, Bangladesh during May 2007 to May 2008. To ensure appropriate treatment, knowledge of the organisms that cause specific infection and their antibiotic susceptibility is mandatory. In the present study, 40 isolates of E.coli were analyzed in term of antibiotic susceptibility. Result of antimicrobial susceptibility test reveals that all of the isolates were sensitive to Cotrimoxazole (30.0%), Ciprofloxacin (20.0%), Nalidixic acid (10.0%), Ceftriaxone (30.0%), Chloramphenicol (70.0%), Cefuroxime (10.0%), Imepenem (100.0%), Cefixime (70.0%). Multi-drug resistance pattern was observed in 90% of the isolates. 30% isolates were resistant to 8 antibiotics, 40% isolates were resistant to 6 antibiotics, 10% isolates were found to resist 4 antibiotics and 10% isolates were found resistant to 3 antibiotics. Our study concludes that there is a trend towards an increase in resistance to fluoroquinolones in the common gram-negative bacteria. Imipenem is the most active agent against gramnegative bacteria (Escherichia coli).The results of the susceptibility of Escherichia coli causing bacteremia provide valuable information for implementing the appropriate chemotherapy for bacteremia.Download


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